PMID:19258539, Establishing health benefits of bioactive food components: a basic research scientist's perspective, USDA-ARS?s Scientific Manuscript database.

Such resources support the search for information about single compounds and facilitate the introduction of secondary analyses of large datasets. In vitro bioactivity of two sodium-free glasses based on the quaternary system SiO 2 -P 2 O 5 -CaO-CaF 2 with 0 and 4.5 mol% CaF 2 content was investigated and compared with the sodium containing glasses with equivalent amount of CaF 2 . Nutrients have shown to affect gene expression and to induce changes in DNA and protein molecules. Importantly, the anti-proliferative and apoptosis-inducing effects of neem components are tumor selective as the effects on normal cells are significantly weaker. Results of the microscopic examination of the urine collected from the urostomy pouch of the patient showed a food debris-like component. This contribution focus on the bioactive peptides derived from marine organisms and elaborates its possible prevention and therapeutic roles in NCD. In recent years, Antrodia cinnamomea has attracted great attention around the world as an extremely precious edible and medicinal mushroom. -[p-(1,1,3,3-Tetramethylbutyl)phenyl]-omega hydroxypoly 21 Food and Drugs 3 2014-04-01 2014-04-01 false Components of paper and paperboard in contact with preservative in coatings and sizings. (pequi), Dipteryx alata Vog. LDL-cholesterol levels (p < 0.01). We detected multiple glycated proteoforms together with potentially toxic advanced glycation end products (AGEs) derived from lunasin. The applications of nanotechnology in food industry. PMID:26473827. In conclusion, CPH (60-85% DH) had the greatest bioactive potential and lowest reactivity to tropomyosin, compared with other CPH and the unhydrolyzed control. The objective of this study was to develop a microwave heat transfer model to predict spatial and temporal profiles of various heterogeneous foods such as multi-component meal (chicken nuggets and mashed potato), multi-component and multi-layered meal (lasagna), and multi-layered food with active packages (pizza) during microwave heating. Fermented rice bran extracts from three rice varieties reduced growth of human B lymphomas compared to each varietys nonfermented control and revealed that fermentation differentially altered bioactive compounds. The total phenolic contents, the scavenging activities against DPPH, oxygen, hydroxyl and ABTS cation radicals, and cell-based antioxidant activities were determined for the antioxidant capacities. In addition, the herbal sources of 32 chromatographic peaks were identified through comparative studying on chromatograms of standard, the respective extracts of Hongdoushan, RenShen, GanCao, and CHC. The increased life expectancy and the expansion of the elderly population are stimulating research into aging. Therefore leaves and roots extracts of those species were evaluated for radical scavenging (RSA) and metal chelating activities, and for invitro inhibition of acetyl-(AChE) and butyrylcholinesterase (BuChE). PMID:22072996. Polysulfone and bioactive glass particulate were combined in composites with different volume fractions. While microalgae-derived polyunsaturated fatty acid (PUFA) and their roles in promoting human health have been extensively studied, other lipid types from this resource, such as phytosterols, have been poorly explored. Copyright 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Therefore, incorporating these components into the regular diets of individuals is justified, because they contribute additional positive effects. In near future, suitably developed and implemented bio/chemosensoristic devices will be a new and modern technological solution for the identification of new quality and safety marker indexes as well as for a more proper and complete characterization of abovementioned environmental and food matrices. Oligosaccharides (prebiotic effect) and bioactive compounds (antioxidant effect) are important constituents of dietary fibre, which enhance its beneficial effects in the body, such as those related to maintaining intestinal health. Some agricultural and industrial residues have proven to be excellent choices as raw materials for producing bioactive compounds and have been proposed as potentially safe natural sources of antimicrobials and/or antioxidants for the food industry. Polysaccharides (PSs) are an important component of mushrooms, a major factor in their bioactive properties, and have been intensively studied during the past two decades. The body will signal thirst before dehydration occurs to prevent problems with fluid loss. G. divaricata (L.) DC belongs to genus the Gynura Cass which is a kind of perennial herb that has good health protection efficacy and is especially used widely in medicine and functional food. The modern day consumer tends to choose products with health enhancing properties, enriched in bioactive substances. This socio-economic activity generates a large amount of solid waste (up to 30%, w/w of the material used). This article reviews isolation of OHD and OHG from non-synthetic sources and production of the compounds by genetically modified microorganisms. Karmaus, Agnes L; Filer, Dayne L; Martin, Matthew T; Houck, Keith A. Diels, Aloe barbadensis Miller, and Dimocarpus longan Lour. This article summarizes the frontiers of knowledge crossed during four eras of development of bioactive glasses that have led from concept of bioactivity to widespread clinical and commercial use, with emphasis on the first composition, 45S5 Bioglass. Our SF research has been in the development of methods employing supercritical fluid chromatography (SFC) and extraction (SFE) coupled to a Fourier transform infrared (FT-IR) spectrometer to investigate food composition. An appropriate framework is needed for establishing recommended intakes for which public health messages and food labeling for DBCs can be derived, because their putative health benefits may not be readily defined in the context of nutritional essentiality. Bioactive food packaging is an innovative approach for the prevention of the growth of food-spoilage microorganisms. For commercial purposes, their fruiting bodies must obey rigid morphological criteria. Some caution is recommended, however, due to the limitations of current research as well as indications that many nutrients exert biphasic, dose-dependent effects and that genetic polymorphisms may alter outcomes. Punicic acid (PuA; 18: 3 9cis,11trans,13cis ) is an unusual 18-carbon fatty acid bearing three conjugated double bonds. Using the curated bioactive relationships, a bipartite network was reconstructed and the corresponding network (or sub-network) visualization and topological analyses are provided for users. Apart from a brief presentation of the theories of UPE and extraction equipment systems, the principal parameters that influence the extraction efficiency to be optimized in the UPE (e.g., solvent, pressure, temperature, extraction time, and the number of cycle) were discussed in detail, and finally the more recent applications of UPE for the extraction of active compounds from plant materials were summarized. Basic research has identified a number of bioactive factors that are necessary, but not sufficient, for organogenesis. Bioavailability of bioactive food compounds: a challenging journey to bioefficacy. CPH allergenicity was evaluated using human shrimp-allergic sera.

This review summaries the dietary sources and bioactivities of melatonin, with special attention paid to the mechanisms of action. Probiotic Incorporation in Edible Films and Coatings: Bioactive Solution for Functional Foods, Nowadays, the consumption of food products containing probiotics, has increased worldwide due to concerns regarding healthy diet and wellbeing. Rapid rise of computational resources successively, Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity12, Hostetler, Gregory L; Ralston, Robin A; Schwartz, Steven J, Flavones are a class of flavonoids that are a subject of increasing interest because of their biological activities in vitro and in vivo. The increasing efforts to use ingredients that are as natural as possible in the formulation of innovative products has given rise to the introduction of macro and microalgae in food industry. Encapsulation of these fatty acids could create a barrier against reaction with harmful environmental factors. However, with bioactive glass nanoparticles addition, tensile strength and strain were reduced from 22.2 to 12.2MPa and 667.2 to 457.8%, respectively with 25 wt.% of bioactive glass nanoparticles. Food samples were sent overnight to the Food Composition Laboratory of the Linus Pauling Institute at Oregon State University (Corvallis, OR) for bioactive compound analysis. Furthermore, several products present on the market show few benefits and sometimes even the reverse - unhealthy effects; the evidence of efficacy is often unconvincing and epidemiological studies are necessary to prove the truth of their claims. Blanco-Padilla, Adriana; Soto, Karen M.; Hernndez Iturriaga, Montserrat, Natural food antimicrobials are bioactive compounds that inhibit the growth of microorganisms involved in food spoilage or food-borne illness. The biological function of these lipids as regulators of NSC differentiation will be reviewed and their application in stem cell therapy discussed. The increased focus on bitter melon consumption could in part be due to several recent pre-clinical efficacy studies demonstrating bitter melon potential to target obesity/type II diabetes-associated metabolic aberrations as well as its pre-clinical anti-cancer efficacy against various malignancies. Bioactive packaging is gaining more and more interest not only due to its environment friendly nature but also due to its potential to improve food quality and safety during packaging. PMID:28761878. In addition, studies about the extraction of active compounds from natural products have attracted special attention in the last recent years. Moreover, a recent synthetic biology approach to cost effective and consistent production of saffron bioactives has been highlighted.

Opposite stereoselective degradation of the two enantiomers was observed in pak choi, spinach cucumber, and tomato. Variations in gut flora were also analysed in the process of in vitro digestion of pastry products in a bioreactor. Won, Keehoon; Jang, Nan Young; Jeon, Junsu. PMID:26184233. Chen, Jianhui; Zeng, Lei; Chen, Xiaofeng; Liao, Tianshun; Zheng, Jiafu. A number of unique biological and pharmacological activities including anti-angiogenic, anticancer, anticoagulant, anti-hypertension, anti-inflammatory, antimicrobial, antioxidant, antithrombotic, antitumor and wound healing have been ascribed to various species of sea cucumbers. The bioactive components in the formula were identified by evaluating the molecular similarity between the components in formula and the components that influence the TF of DEGs. Fresh, processed fruits and vegetables including frozen and canned, cooked, 100% fruit juices and 100% vegetable juices, as well as dry fruits are all considered as servings of fruits and vegetables per day. Bioactive Encapsulation for Military Food Applications: Request for Enhanced Nano and Micro Particle Fabrication and Characterization Facilities, 2013 21-Jul-2014 Approved for Public Release; Distribution Unlimited Final Report: Bioactive Encapsulation for Military Food Applications: Request forreviewed journals: Number of Papers published in non peer-reviewed journals: Final Report: Bioactive Encapsulation for Military Food ApplicationsTotal Number: Inventions (DD882) Scientific Progress Equipment was purchased. Here we have determined multiple bioactive components in SHXXT and investigated the comparative pharmacokinetics of rhein in rats. Microwave treatment increased -amylase inhibitor concentration, activity and potency, which were strongly correlated (r =0.71, P < 0.0001) with the flavonol content of beans. The concentrations of ferulic acid, caffeic acid, vanillic acid, ligustilide, paeoniflorin, albiflorin and oxypaeoniflorin in rat plasma and the concentrations of ferulic acid, vanillic acid, paeoniflorin, albiflorin and oxypaeoniflorin in tissues were determined by UPLC-MS/MS. Especially, the values of ferric-reducing antioxidant power (FRAP), trolox equivalent antioxidant capacity (TEAC) and TPC in the residues were higher than in pulps. The root mean square error values of temporal profiles ranged from 5.8 C to 26.2 C in chicken nuggets as compared 4.3 C to 4.7 C in mashed potatoes. Principal components analysis (PCA) was employed to analyze hedonic ratings of the foods, to identify component structures and to reduce the number of variables. Global DNA hypomethylation, gene promoter hypermethylation and aberrant histone post-translational modifications are hallmarks of neoplastic cells which have been associated with genomic instability and altered gene expression. Corra, Rbia Carvalho Gomes; de Souza, Aloisio Henrique Pereira; Calhelha, Ricardo C; Barros, Lillian; Glamoclija, Jasmina; Sokovic, Marina; Peralta, Rosane Marina; Bracht, Adelar; Ferreira, Isabel C F R. Pleurotus ostreatoroseus is a Brazilian edible mushroom whose chemical characterization and bioactivity still remain underexplored. The TFs of DEGs were derived from GeneCards. Chen (Sanqi in Chinese) is one of traditional Chinese medicines (TCMs) based functional food.

For an in depth understanding of food processing in the gastrointestinal tract, it is necessary to apply multidisciplinary methodologies, at the interface between materials science, chemistry, physics and biology. Recently, it was developed to extract bioactive ingredients from plant materials, known as ultrahigh pressure extraction (UPE), taking advantages of time saving, higher extraction yields, fewer impurities in the extraction solution, minimal heat and can avoid thermal degradation on the activity and structure of bioactive components, and so on. What are the 3 natural forms of vitamin B6? External validation of the scales is recommended, since they provide an instrument capable of capturing useful information for monitoring and evaluating the Child-care Centers program nation-wide, from the perspective of program managers and parents of program users. Zhang, Hao; Yu, Dandan; Sun, Jing; Liu, Xianting; Jiang, Lu; Guo, Huiyuan; Ren, Fazheng. Further study of this phenomenon could contribute to the development of new strategies to extend algal production cycles in open, outdoor systems while ensuring the, Sol-gel derived porous bioactive nanocomposites: Synthesis and in vitro bioactivity. The compressive strength of the composite loaded with gentamicin sulfate decreased from the as-fabricated value of 24 3 MPa to ~8 MPa after immersion for 14 days in PBS. Using the formula of Tian-Zhu-San (TZS) as an example, the reliability and limitation of ITPI were examined and 16 bioactive components that influence TFs were identified. 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2018. The extracted oil from agarwood leaves by soxhlet extraction was analyzed using gas chromatography mass spectrometry. The results showed that different fruit residues had diverse antioxidant potency and the variation was very large. In the United States, dietary reference intakes describe the relations between nutrient intakes and indicators of adequacy, prevention of disease, and avoidance of excessive intakes among healthy populations for essential nutrients but not dietary bioactive components (DBCs), whose absence from the diet is presumably not deleterious to health (i.e., does not cause a deficiency syndrome). In recent years, it has been recognized that many dietary constituents may contribute to human cardiovascular health. Enteric nutrition formulas supplemented with transforming growth factor , a milk cytokine, have been shown to promote remission in pediatric Crohn's disease. The banana hemagglutinin exhibited highest activity between pH 7 and 8, and it was inhibited by high concentrations of glucosamine, galactosamine, and, to a lesser extent, mannosamine. Suleria, H A R; Masci, P P; Gobe, G C; Osborne, S A. Upon oral administration and absorption, soy-derived bioactive peptides may induce several physiological responses such as antioxidative, antimicrobial, antihypertensive, anticancer and immunomodulatory effects. PMID:29876353. The prepared and soaked specimens were characterized using Fourier transform infrared spectroscopy, X-ray diffractometry and scanning electron microscopy. The feasibility and credibility of this methodology were also assessed with a developed fast HPLC method. Nowadays, bioactive peptides production, its isolation, characterization, and strategies for its delivery to target sites are a matter of intensive research. DNA methylation profile may change under the influence of diet, single nucleotide polymorphisms and environmental factors. These seeds are a legacy of pre-Columbian civilizations reason why in our time they are considered as "Superfoods of the Gods", "The pre-hispanic superfoods of the future" and "The new golden seeds of the XXI century". This review describes an alternative approach focusing upon development of tomato-based food products for human clinical trials targeting cancer prevention and as an adjunct to therapy. Ultrahigh pressure extraction of bioactive compounds from plants-A review. 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. Is lactate an undervalued functional component of fermented food products? Recent trends in functional foods have evidenced that food bioactive proteins play a major role in the concepts of illness and curing; therefore, nutritionists, biomedical scientists, and food scientists are working together to develop improved systems for the discovery of peptides with increased potency and therapeutic benefits. As a result, 26 bioactive components originated from JTT and 5 metabolites were tentatively identified in orally dosed rat plasma by comparing their retention times and MS spectra with those of authentic standards and literature data. A Food Debris-Like Component in the Urine Sediment From a Urostomy Pouch. The discovery of such novel bioactive compounds is expected to encourage further studies which can potentially lead to tapping of the antibiotic production potential of this fascinating group of microorganisms.Anaerobes are widely used in preparation of fermented foods and beverages.

The purpose of this study was to estimate the intake of selected bioactive compounds from fennel-containing plant food supplements (PFS) among Finnish consumers. Bioactivity was assessed by the immersion of the samples in simulated body fluid for different intervals. Blood and breast tissue were collected to determine drug/metabolite concentrations and limonene-induced changes in systemic and tissue biomarkers of breast cancer risk or carcinogenesis. We discuss their fate in a wide variety of engineered, processed and naturally-occurring foods as they pass through the gastrointestinal tract and the implicit role of the food matrix within which they reside. Virgin olive oil, the main fat of the Mediterranean diet, is per se considered as a functional food-as stated by the European Food Safety Authority (EFSA)-due to its content in healthy compounds. Since the available evidence is pointing toward the possible health benefits of oat and barley components, a number of authors have examined techniques for recovering them from their native sources. Phenolics and flavonoids were also determined and were found to increase during drying below 50 C. Sequential Proton Loss Electron Transfer in Deactivation of Iron(IV) Binding Protein by Tyrosine Based Food Components. 2016 The Authors. However, we show that the glass structure is an important parameter in determining T(g). PMID:26011900. Taking vitamin or mineral supplements just before competition will help to improve performance. Free-radical scavenging activity was evaluated by spraying thin-layer chromatography plates (spotted with fractions) with 0.2% of 2,2-diphenyl-1-picrylhydrazyl solution. Johnson, Susan L.; Boles, Richard E.; Burger, Kyle S. Theorists posit that food reward is a powerful determinant of intake, yet little is known regarding how individuals hedonic ratings of a variety of foods interrelate and how hedonic ratings correspond to habitual dietary intake. Previous studies have also shown that medicinal plant polysaccharides are non-toxic and show no side effects. In addition, ellagitannins were one of the distinguishing compound classes in strawberry leaves. Previously, it was thought that functional ingredients such as non-starchy carbohydrates including soluble and insoluble dietary fibres, fucoidan; antioxidants including polyphenols, carotenoids, tocopherols, tocotrienols, phytosterols, isoflavones, organosulphur compounds; plant sterols and soy phytoestrogens occur only in plant foods (whole grains, fruits, and vegetables) as phytochemicals. After adjustment for changes in body weight and SPA, 24-h EE was increased by 160 kJ/day (95% CI: 15-305) by the simple preparation as compared to placebo, whereas the enterocoated preparation had no such effect (53 kJ/day, -92 to 198); simple vs enterocoated versions (P=0.09). Bioactive peptides derived from food sources have the potential for incorporation into functional foods and nutraceuticals. Nutritionally, sea cucumbers have an impressive profile of valuable nutrients such as Vitamin A, Vitamin B1 (thiamine), Vitamin B2 (riboflavin), Vitamin B3 (niacin), and minerals, especially calcium, magnesium, iron and zinc. Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer. Layer-by-Layer assembled protein-tannic acid (TA) films are suggested as a prospective material for microencapsulation of food-derived bioactive compounds. They are commercially valuable and prized as a food and folk medicine in Asia. None of the tested strains produced harmful enzymes (-glucosidase and -glucuronidase) or biogenic amines. Chakrabarti, Subhadeep; Jahandideh, Forough; Wu, Jianping. Bioactivity of the glasses was investigated in vitro by examining apatite formation on the surface of glasses treated in acellular simulated body fluid (SBF) with ion. This mini review discusses relevant patents and gives an overview on bioactive proteins and peptides obtainable from soybeans. A very active research to identify functional foods and their components that are generally recognised as safe has been ongoing, with the aim of developing alternative approaches, to the use of synthetic chlorhexidine, and at the reduction or prevention of caries. Chemical profiling of test Wedelia species demonstrated candidate index compounds and distinguishable secondary metabolites, such as caffeic acid derivatives, which may serve as phytochemical markers or index for quality control and identification of specific Wedelia species. However, this mechanism of action has not been fully validated because THI does not inhibit S1PL invitro. The source of valid nutrition information is: Your best friend tells you that she has started taking vitamin supplements to give her energy. In ruminants, they are responsible for producing abundant amounts of methane during digestion of food, but selected bioactive plants and compounds may inhibit this activity. PMID:19158015.

Rice Varietal Differences in Bioactive Bran Components for Inhibition of Colorectal Cancer Cell Growth. Among the 12 strains, 3 strains were tested for their cytotoxic effects against 3 cancer cell lines, which exhibited strong cytotoxic effects, and they also showed selectivity in killing cancer cells when compared to normal cells. HPP-treated samples showed higher tocopherol and carotenoid bioaccessibility than TT-treated samples, thus indicating that HPP combined with a milk matrix positively modulates the bioaccessibility of certain types of bioactive components of food, mainly those of a lipophilic nature.

Some of them have been regarded as promising therapeutic agents and approved into clinical trial by the U.S. Food and Drug Administration. Food nanotechnology could create modem convenience foods that mimic and improve on the nutritional value of the most nutritious cooked wild foods for humans. Design of microwavable food can be realized through a simulation model which describes the physical mechanisms of microwave heating in mathematical expressions. Mesoporous bioactive glass (MBG) modified -tricalcium phosphate (MBG--TCP) scaffolds with a hierarchical pore structure and a functional strut surface (~100 nm of MBG nanolayer) were successfully prepared via 3D printing and spin coating. The main food components--carbohydrates, proteins and fatty acids--were implemented in an in vitro digestion process to simulate realistic conditions.